Journal of Advanced Pharmacy Education & Research
 
 
Year : 2014   |  Volume : 4   |  Issue : 2   |  Page : 240-246  

Anticancer activity of ethanol extract of Asystasia travancorica Bedd (Acanthaceae) whole plant against Dalton Ascites Lymphoma

Komalavalli.T, Packia Lincy. M, Muthukumarasamy. S Mohan V.R

Correspondence Address:1Obsteterics & Gynecology Department Government Siddha Medical College, Palayamkottai- 627002, Tamilnadu. 2Ethnopharmacology Unit, Research Department of Botany, V. O. Chidambaram College, Tuticorin, 628 008, Tamil Nadu, India. 3Department of Botany, Sri K.G.S. Arts College, Srivaikuntam, Tamil Nadu, India.

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-4040.197331

Abstract  

The present study aims to evaluate the antitumor activity of ethanol extract of whole plant of Asystasia travancorica Bedd on DAL induced tumor in Swiss Albino mice. Evaluation of the antitumor effect of ethanol extract of whole plant of Asystasia travancorica on tumor growth and host survival time was made by the study of the following parameters: tumor volume, viable and non viable cell count and life span of host. The results showed decrease in tumor volume and viable cell count. Hematological studies revealed that, the Hb count decreased in DAL treated mice, whereas it was induced by the drug treated animals and showed an increase in Hb near to normal levels. The results suggested that the extract of whole plant of Asystasia travancorica exhibited significant antitumor activity on DAL bearing mice.

Keywords: Asystasia travancorica, antitumor, lifespan, WBC, DAL, HB.

How to cite this article:
: Komalavalli.T1

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