Journal of Advanced Pharmacy Education & Research
Year : 2012   |  Volume : 2   |  Issue : 3   |  Page : 110-127  

Metal-organic frame works of transition metal Co (II), Ni (II), Zn (II), Cd (II) and Cu (II) ions derived from streptomycin and chloramphenicol and their molecular modeling

Parashuram Mishra and Kalpna Mishra

Correspondence Address:Bioinorganic and Materials Chemistry Research Laboratory, Department of Chemistry, Tribhuvan University, M.M.A.M. Campus, Biratnagar, India

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2231-4040.197331


Metal organic frame works of transition metal ions complexes have been synthesized with streptomycin and oxime. Conformational changes and binding abilities of the organic frame works toward metal ions were identified by various physical -chemical and spectroscopic measurements including IR, 1HNMR, UV-Vis, molecular modeling and X-ray powder diffractometery. The lattice parameters were calculated by CRYSFIRE software programme. Molecular model represent a better understanding of the arrangement of the atoms in the molecules in three dimensions. The synthesized complexes were highly antibacterial effective.

Keywords: Antibiotic, streptomycin, chloramphenicol, TGA, molecular modeling

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Introduction   Top

Materials and methods   Top

Results Discussion   Top

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Acknowledgement   Top

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